4-Amino-2,6-diphenylphenol → 2-[1-(2,4,6-Trimethylphenylimino)ethyl]-6-[1-(4-hydroxy-3,5-diphenylphenylimino)ethyl]pyridine

HRID 1986031Notes

Reaction equation

HRID 1986031 reaction equation
OC1C(C2C=CC=CC=2)=CC(N)=CC=1C1C=CC=CC=1.CC1C=C(C)C=C(C)C=1N=C(C1C=CC=C(C(=O)C)N=1)C.[CH3:42][C:43]1[CH:48]=[C:47]([CH3:49])[CH:46]=[C:45]([CH3:50])[C:44]=1[N:51]=[C:52]([C:54]1[CH:59]=[CH:58][CH:57]=[C:56]([C:60](=[N:62][C:63]2[CH:68]=[C:67]([C:69]3[CH:74]=[CH:73][CH:72]=[CH:71][CH:70]=3)[C:66]([O:75]CCC)=[C:65]([C:79]3[CH:84]=[CH:83][CH:82]=[CH:81][CH:80]=3)[CH:64]=2)[CH3:61])[N:55]=1)[CH3:53]>C1(C)C=CC=CC=1>[CH3:42][C:43]1[CH:48]=[C:47]([CH3:49])[CH:46]=[C:45]([CH3:50])[C:44]=1[N:51]=[C:52]([C:54]1[CH:59]=[CH:58][CH:57]=[C:56]([C:60](=[N:62][C:63]2[CH:68]=[C:67]([C:69]3[CH:70]=[CH:71][CH:72]=[CH:73][CH:74]=3)[C:66]([OH:75])=[C:65]([C:79]3[CH:84]=[CH:83][CH:82]=[CH:81][CH:80]=3)[CH:64]=2)[CH3:61])[N:55]=1)[CH3:53]

Participants

5

Reactant 3

HCID 6215554-Amino-2,6-diphenylphenolHCID 221344681-{6-[(1E)-N-(2,4,6-Trimethylphenyl)ethanimidoyl]pyridin-2-yl}ethan-1-oneHCID 577213892-[1-(2,4,6-Trimethylphenylimino)ethyl]-6-[1-(4-propoxy-3,5-diphenylphenylimino)ethyl]pyridine

Product 1

HCID 1360046952-[1-(2,4,6-Trimethylphenylimino)ethyl]-6-[1-(4-hydroxy-3,5-diphenylphenylimino)ethyl]pyridine

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The title compound was prepared by condensation of 4-hydroxy-3,5-diphenylaniline with 2-[1-(2,4,6-trimethylphenylimino)ethyl]-6-acetylpyridine, prepared according to the method disclosed in WO02/28805, in toluene, using 4 Å molecular sieves, similarly to the above-described preparation of 2-[1-(2,4,6-trimethylphenylimino)ethyl]-6-[1-(4-propoxy-3,5-diphenylphenylimino)ethyl]pyridine.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-a31da377308746f5b302ea1ca2713cf5
Source dataset
uspto-grants-2009_06
Patent number
US07547783B2

Reaction notes

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