HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluoro-2-methylaniline → 2-Fluoro-N-(4-fluoro-2-methylphenyl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluoro-2-methylaniline | HCID 67982 | — |
| Reactant | 2-Fluoro-N-o-tolylnicotinamide | HCID 57721371 | — |
| Product | 2-Fluoro-N-(4-fluoro-2-methylphenyl)nicotinamide | HCID 57721325 | 99% |
Reaction Steps
4-Fluoro-2-methylaniline (Aldrich, 0.18 mL, 1.6 mmol) was converted to the desired compound (0.098 g, 99%) in a manner similar to the preparation of 2-fluoro-N-o-tolylnicotinamide (Step A of Example 8). MS(ESI+) m/z 249 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547782B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-e6ef03d742f44a3fac5f14a252a07692 |
| Source note | uspto-grants-2009_06 |