HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloroaniline → N-(2-Chlorophenyl)-2-fluoronicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloroaniline | HCID 7240 | — |
| Reactant | 2-Fluoro-N-o-tolylnicotinamide | HCID 57721371 | — |
| Product | N-(2-Chlorophenyl)-2-fluoronicotinamide | HCID 57721372 | 84% |
Reaction Steps
2-Chloroaniline (Aldrich, 0.17 mL, 1.6 mmol) was converted to the desired compound (0.084 g, 84%) in a manner similar to the preparation of 2-fluoro-N-o-tolylnicotinamide (Step A of Example 8). MS(ESI+) m/z 251 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547782B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-e058b416afca4bddbe3dc57b43993759 |
| Source note | uspto-grants-2009_06 |