HRID1986211

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID86625342

未命名化合物

结构：COc1ccc(C(NC(=O)c2cccc3sc(-c4nc(Cl)ncc4C)cc23)c2ccc(OC)cc2)cc1

HCID86625359

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(NC(=O)c2cccc3sc(-c4nc(Cl)ncc4Br)cc23)c2ccc(OC)cc2)cc1

HCID86625358

未命名化合物

PROCEDURE

实验过程

Using the method of 2-(2-chloro-5-methylpyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid [bis-(4-methoxyphenyl)-methyl]-amide, the title compound is synthesized from 2-(5-bromo-2-chloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid as a tan solid.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-eeba1b82d44e452ba9c05c9376f546ae
来源数据集: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07547691B2
来源说明: uspto-grants-2009_06

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([NH:18][C:19]([C:21]2[C:29]3[CH:28]=[C:27]([C:30]4[C:35](C)=[CH:34][N:33]=[C:32]([Cl:37])[N:31]=4)[S:26][C:25]=3[CH:24]=[CH:23][CH:22]=2)=[O:20])[C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=2)=[CH:5][CH:4]=1.[Br:38]C1C(C2SC3C=CC=C(C(O)=O)C=3C=2)=NC(Cl)=NC=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]([NH:18][C:19]([C:21]2[C:29]3[CH:28]=[C:27]([C:30]4[C:35]([Br:38])=[CH:34][N:33]=[C:32]([Cl:37])[N:31]=4)[S:26][C:25]=3[CH:24]=[CH:23][CH:22]=2)=[O:20])[C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=2)=[CH:5][CH:4]=1