5-Ethynylpyridin-2-amine → 5-[8-Methyl-6-(4-trifluoromethyl-phenyl)-imidazo[1,2-a]pyridin-3-ylethynyl]-pyridin-2-ylamine
Reaction equation
[C:22](#[CH:23])[c:24]1[cH:25][cH:26][c:27]([NH2:30])[n:28][cH:29]1.[I:1][c:2]1[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8](-[c:12]1[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[cH:9][c:10]2[CH3:11]>>[c:2]1([C:23]#[C:22][c:24]2[cH:25][cH:26][c:27]([NH2:30])[n:28][cH:29]2)[cH:3][n:4][c:5]2[n:6]1[cH:7][c:8](-[c:12]1[cH:13][cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1)[cH:9][c:10]2[CH3:11]Participants
3
Sources & evidence
- ORD record
- ord-fb57360615ca4a0484b301da918f52e2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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