7-Bromobenzo[b]thiophene → HCID 68859112, compound

HRID 1986254Notes

Reaction equation

HRID 1986254 reaction equation
Cl.Cl.Cl.Br[C:5]1[CH:6]=[CH:7][C:8]2[CH:12]=[C:11]([C:13]3[C:18]([CH3:19])=[CH:17][N:16]=[C:15]([NH:20][CH2:21][CH2:22][CH2:23][N:24]4[CH2:29][CH2:28][N:27]([CH3:30])[CH2:26][CH2:25]4)[N:14]=3)[S:10][C:9]=2[CH:31]=1.[Br:32]C1C2SC=CC=2C=CC=1>>[Br:32][C:31]1[C:9]2[S:10][C:11]([C:13]3[C:18]([CH3:19])=[CH:17][N:16]=[C:15]([NH:20][CH2:21][CH2:22][CH2:23][N:24]4[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]4)[N:14]=3)=[CH:12][C:8]=2[CH:7]=[CH:6][CH:5]=1

Participants

3

Reactant 2

HCID 120455387-Bromobenzo[b]thiopheneHCID 68856220[4-(6-Bromobenzo[b]thiophen-2-yl)-5-methylpyrimidin-2-yl]-[3-(4-methylpiperazin-1-yl)-propyl]-amine tri-hydrochloride

Product 1

HCID 68859112HCID 68859112, compound

Procedure

Using the method of [4-(6-bromobenzo[b]thiophen-2-yl)-5-methylpyrimidin-2-yl]-[3-(4-methylpiperazin-1-yl)-propyl]-amine tri-hydrochloride, the title compound is prepared from 7-bromobenzo[b]thiophene and isolated as a solid. ES+(m/z) 460 (79Br) and 462 (81Br) [M+H].

Workup

  1. customisolated as a solid

Sources & evidence

ORD record
ord-44f964ff901b47e1b83a91ec40077654
Source dataset
uspto-grants-2009_06
Patent number
US07547691B2

Reaction notes

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