反应详情

Using the method of 2-[5-chloro-2-(2-piperidin-4-yl-ethylamino)-pyrimidin-4-yl]-benzo[b]thiophene-4-carboxylic acid cyclopropylamide di-hydrochloride, the title compound is synthesized as a di-hydrochloride salt from 2-(2,5-dichloropyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide and racemic 3-(3-aminopropyl)-piperidine-1-carboxylic acid tert-butyl ester. ES+(m/z) 470 (35Cl) and 472 (37Cl) [M(free base)+H].