huagongshe.com
HRID1986317

反应详情

EQUATION

反应方程式

HRID 1986317 的结构方程式

REACTANTS

反应物

2
结构：CN1CCC(CCNc2ncc(Cl)c(-c3cc4c(C(N)=O)cccc4s3)n2)CC1.Cl.Cl
HCID68856045

未命名化合物

结构：Cc1cnc(NCCN2CCNC[C@H]2C)nc1-c1cc2c(C(=O)NC3CC3)cccc2s1
HCID68857496

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cnc(NCCN2CCN(C)C[C@H]2C)nc1-c1cc2c(C(=O)NC3CC3)cccc2s1.Cl.Cl.Cl
HCID68856119

未命名化合物

PROCEDURE

实验过程

Using the method of 2-{5-chloro-2-[2-(1-methylpiperidin-4-yl)-ethylamino]-pyrimidin-4-yl}-benzo[b]thiophene-4-carboxylic acid amide di-hydrochloride, the title compound is synthesized from (R)-2-{5-methyl-2-[2-(2-methylpiperazin-1-yl)-ethylamino]-pyrimidin-4-yl}-benzo[b]thiophene-4-carboxylic acid cyclopropylamide and isolated as a yellow solid. ES+(m/z) 465 [M(free base)+H].

WORKUP

后处理

  1. customisolated as a yellow solid