HCID 86605664, compound → HCID 86605663, compound

Participants

Reaction Steps

A solution of tert-butyl (2-{[3-(aminomethyl)-2-isobutyl-4-(4-methylphenyl)-6-quinolinyl]oxy}ethoxy)acetate p-toluenesulfonic acid salt (0.2 g, 0.3 mmol) in trifluoroacetic acid (5 ml) was stirred at room temperature for 4 hrs. The reaction mixture was concentrated under reduced pressure and the residue was solidified from diethyl ether. The obtained solid was dissolved in methanol and concentrated under reduced pressure. The residue was again solidified from diethyl ether to give the title compound (0.15 g, yield 83%) as an amorphous form.

Provenance & Evidence