HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Acetate → HCID 86623587, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 1,3,4,5,6,7-Hexahydro-β,1,1,5,5-pentamethyl-2H-2,4a-methanonaphthalene-8-ethanol | HCID 68852524 | — |
| Reactant | HCID 178418287 | HCID 178418287 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86623587 | HCID 86623587 | 64% |
Reaction Steps
Sodium acetate (0.1 g) and PCC (6.6 g, 0.031 mol, portionwise) was added successively at r. t. to a vigorously stirred solution of 3b (6.0 g, 0.023 mol) in dichloromethane (200 ml). After additional 3 h stirring, the black reaction mixture was filtered through Celite®, the filtrate was concentrated in vacuo and purified by flash chromatography (MTBE/hexane 1:10) to give 2-(2,2,7,7-tetramethyltricyclo[6.2.1.01,6]undec-5-en-5-yl)propanal (9b, 3.8 g, 64% yield, white solid).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07550417B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-070e5dc3a05e4aa98c3a3e7f7afddcce |
| Source note | uspto-grants-2009_06 |