Hydrochloric Acid → HCID 57722268, compound

Participants

Reaction Steps

0.466 ml of THF, 38.7 mg (86.66 μmol) of product 10 and then 0.932 ml of HCl (1N) are successively introduced into a round-bottomed flask equipped with a magnetic stirrer. After 50 minutes, the reaction medium is evaporated to dryness. The residue obtained is purified by chromatography on 2 preparative silica plates (20×20 cm, e=0.5 mm, Merck), eluent: CH2Cl2/MeOH (96/4). 14 mg (40%) of product Example 3 are collected.

Provenance & Evidence