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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1986568Generated: October 26, 2026

Piperazine → 3-Chloro-6-piperazin-1-yl-11H-dibenzo[b,e]azepine

https://huagongshe.com/reaction/1986568

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazineHCID 4837—
Reactant3-Chloro-5,11-dihydro-dibenzo[b,e]azepin-6-oneHCID 57485432—
Product3-Chloro-6-piperazin-1-yl-11H-dibenzo[b,e]azepineHCID 11289917—

Reaction Steps

3-Chloro-5,11-dihydro-dibenzo[b,e]azepin-6-one (189JO59) (25 mg, 0.1 mmol) and piperazine were reacted according to GP4 to give 2.2 mg of the title compound (189JO60). MS(ESI) 312 (MH+). Purity for MH+ (UV/MS) 100/100.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07550454B2
Source datasetuspto-grants-2009_06
ORD IDord-2ec63db4cd644b5eacb862e2b5431207
Source noteuspto-grants-2009_06