HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → HCID 11637267, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | HCID 178432402 | HCID 178432402 | — |
| Product | HCID 11637267 | HCID 11637267 | — |
Reaction Steps
A mixture of 5-methyl-6-cyclopentyl-7-hydroxy[1,2,4]triazolo[1,5-a]pyrimidine (17 g, Ex. 2) and POCl3 (50 ml) was heated under reflux for 8 hours. During this operation, some of the POCl3 was distilled off. The residue was poured into a mixture of dichloromethane and water. The organic phase was separated off and dried. Removal of the solvent gave 11 g of the title compound of m.p. 87° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07550471B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-90a1eb9386714ac5b38c7442dba9946b |
| Source note | uspto-grants-2009_06 |