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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1986806Generated: November 1, 2026

Sodium Iodide → HCID 68908687, compound

https://huagongshe.com/reaction/1986806

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium IodideHCID 5238—
ReactantDimethylformamideHCID 6228—
ReactantPotassium CarbonateHCID 11430—
Reactant3-Butyl-8-azabicyclo[3,2,1]octaneHCID 68907966—
ProductHCID 68908687HCID 68908687—

Reaction Steps

Crude (R,S)-1-(3-chloro-2-methylpropyl)-3,4-dihydro-1H-quinolin-2-one (107LH63) (0.094 g), 3-butyl-8-azabicyclo[3.2.1]octane (0.025 g, 0.15 mmol), NaI (0.100 g, 0.67 mmol), and K2CO3 (0.075 g, 0.54 mmol) in DMF (1 mL) were reacted and purified according to GP20 to give the title compound (107LH74-c4) (0.025 g). HPLC-MS (ammonium acetate) [M+H]+=369.33.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07550459B2
Source datasetuspto-grants-2009_06
ORD IDord-b8be9109767f4d159faf320eec81ea82
Source noteuspto-grants-2009_06