HCID 16727123, compound → HCID 57722634, compound

HRID 1986867Notes

Reaction equation

HRID 1986867 reaction equation
[Cl:1][C:2]1[CH:26]=[CH:25][CH:24]=[CH:23][C:3]=1[CH2:4][NH:5][C:6]1[N:11]=[C:10]([NH:12][CH2:13][CH:14]2[CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)[C:9]([N+:20]([O-:22])=[O:21])=[CH:8][N:7]=1.NCC1CCC(C[NH:36][C:37]2C([N+]([O-])=O)=CN=C(NCC3C=CC=CC=3Cl)[N:38]=2)CC1>>[Cl:1][C:2]1[CH:26]=[CH:25][CH:24]=[CH:23][C:3]=1[CH2:4][NH:5][C:6]1[N:11]=[C:10]([NH:12][CH2:13][CH:14]2[CH2:15][CH2:16][N:17]([C:37]([NH2:38])=[NH:36])[CH2:18][CH2:19]2)[C:9]([N+:20]([O-:22])=[O:21])=[CH:8][N:7]=1

Participants

3

Reactant 2

HCID 16727123HCID 16727123, compoundHCID 44440525HCID 44440525, compound

Product 1

HCID 57722634HCID 57722634, compound

Procedure

This compound was prepared in an analogous fashion to Example 9 using N2-(2-Chloro-benzyl)-5-nitro-N4piperidin-4-ylmethyl-pyrimidine2,4-diamine (Example 11) as a starting material in place of N4-(4-Aminomethyl-cyclohexylmethyl)-5-nitro-N2-(2-chloro-benzyl)-pyrmidine-2,4-diamine, m/z calculated for C18H23ClN8O2: 418.0 found: 419.1 (M+H)+.

Sources & evidence

ORD record
ord-a8e73a84f1c9471e993080250f90c7f7
Source dataset
uspto-grants-2009_06
Patent number
US07550473B2

Reaction notes

Loading…