HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 86613212, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Hydrazoic acid | HCID 24530 | — |
| Reactant | tert-butyl (1S,2S)-1-benzyl-2-hydroxyhexylcarbamate | HCID 86613206 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86613212 | HCID 86613212 | — |
Reaction Steps
Prepared in a manner to similar to intermediate XXII. Step A employed DMF as solvent and 3 equiv of phenol as nucleophile. Steps B and C were substituted with Mitsunobu hydrazoic acid inversion (see Intermediate I step C): ES MS (M+H)=283.6.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07550481B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-798dd78d6a3f4ce9a6418207ebb2d79d |
| Source note | uspto-grants-2009_06 |