3-(Dimethylamino)propyl chloride hydrochloride → HCID 10361494, compound

HRID 1987183Notes

Reaction equation

HRID 1987183 reaction equation
Cl.CN(C)CCCCl.[CH3:9][N:10]([CH3:42])[CH2:11][CH2:12][CH2:13][O:14][CH2:15][C:16]1[N:17](COCC[Si](C)(C)C)[N:18]=[C:19]2[C:25]=1[C:24]1[CH:26]=[CH:27][CH:28]=[CH:29][C:23]=1[S:22][C:21]1[CH:30]=[CH:31][CH:32]=[CH:33][C:20]2=1>>[CH3:42][N:10]([CH3:9])[CH2:11][CH2:12][CH2:13][O:14][CH2:15][C:16]1[NH:17][N:18]=[C:19]2[C:25]=1[C:24]1[CH:26]=[CH:27][CH:28]=[CH:29][C:23]=1[S:22][C:21]1[CH:30]=[CH:31][CH:32]=[CH:33][C:20]2=1

Participants

3

Reactant 2

HCID 943083-(Dimethylamino)propyl chloride hydrochlorideHCID 10345694HCID 10345694, compound

Product 1

HCID 10361494HCID 10361494, compound

Procedure

By the reaction of alcohol 19B (0.15 mmole) and 3-dimethylaminopropylchloride-hydrochloride (1.8 mmole), dimethyl-{3-[2-(2-trimethylsilyl-ethoxymethyl)-2H-8-thia-1,2-diaza-dibenzo[e,h]azulene-3-ylmethoxy]-propyl}-amine in the form of an oily product was obtained.

Workup

  1. customwas obtained

Sources & evidence

ORD record
ord-bf6ef968cb674b27a1909980f45ee26c
Source dataset
uspto-grants-2009_06
Patent number
US07550498B2

Reaction notes

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