Cyclohexylamine → HCID 68852776, compound

HRID 1987408Notes

Reaction equation

HRID 1987408 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([C:12]2([OH:18])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:9]([OH:11])=O)[CH:5]=[CH:6][CH:7]=1.[CH:19]1([NH2:25])[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]([C:12]2([OH:18])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)[C:9]([NH:25][CH:19]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)=[O:11])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 7965CyclohexylamineHCID 68853928(3-Chlorophenyl)(1-hydroxycyclohexyl)acetic acid

Product 1

HCID 68852776HCID 68852776, compound

Procedure

In an analogous manner to Example 1, step 1 2-(3-chlorophenyl-N-cyclohexyl-2-(1-hydroxycyclohexyl)acetamide was prepared from (3-chlorophenyl)(1-hydroxycyclohexyl)acetic acid (Reference Example 1-a) and cyclohexylamine. MS (ESI) m/z 350/352 ([M+H]+).

Sources & evidence

ORD record
ord-99047e1606b140cf96ad711be468f700
Source dataset
uspto-grants-2009_06
Patent number
US07550485B2

Reaction notes

Loading…