Potassium Cation → 3'-Chloro-7'-(2-fluoro-3-pyridinyl)spiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine

HRID 198759Notes

Reaction equation

HRID 198759 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:14]([cH:15][cH:16]1)[O:13][c:7]1[c:6]([cH:11][c:10]([Cl:12])[n:9][cH:8]1)[C:5]21[CH2:17][O:18][CH2:19][C:20]([NH2:22])=[N:21]1.[F:23][c:24]1[n:25][cH:26][cH:27][cH:28][c:29]1[B:30]([OH:31])[OH:32].[K+:38].[K+:39].[K+:40].[P:33]([O-:34])([O-:35])([O-:36])=[O:37]>>[c:2]1(-[c:29]2[c:24]([F:23])[n:25][cH:26][cH:27][cH:28]2)[cH:3][c:4]2[c:14]([cH:15][cH:16]1)[O:13][c:7]1[c:6]([cH:11][c:10]([Cl:12])[n:9][cH:8]1)[C:5]21[CH2:17][O:18][CH2:19][C:20]([NH2:22])=[N:21]1

Participants

5

Reactant 4

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 27832702-Fluoropyridine-3-boronic acidHCID 584659017-Bromo-3-chloro-2',6'-dihydrospiro[chromeno[2,3-c]pyridine-5,3'-[1,4]oxazin]-5'-amine

Product 1

HCID 874008433'-Chloro-7'-(2-fluoro-3-pyridinyl)spiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine

Sources & evidence

ORD record
ord-8a0dd6e09c54476daf2123f6a906b14e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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