反应详情

Example 20 was synthesized from (Z)-4-(4-chloroquinolin-2(1H)-ylidene)-3-isopropyl-1H-pyrazol-5(4H)-one and 4-aminothiophenol according to the procedure described in Example 19. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.00 (bs, 6H) 3.33 (bs, 1H) 5.87 (s, 1H) 6.78 (d, J=8.34 Hz, 2H) 7.31 (d, J=8.34 Hz, 2H) 7.52 (bs, 1H) 7.77 (bs, 1H) 8.03 (d, J=8.34 Hz, 1H); ESI-MS: m/z calc'd for C21H20N4OS 376.47. found 377.2 (M+H)+.