Quinoline 1-oxide → HCID 178486268, compound

HRID 1987640Notes

Reaction equation

HRID 1987640 reaction equation
[CH3:1][NH:2][S:3]([C:6]1[CH:11]=[CH:10][C:9]([C:12]2[CH2:16][C:15](=[O:17])[NH:14][N:13]=2)=[CH:8][CH:7]=1)(=[O:5])=[O:4].[N+:18]1([O-])[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[CH:21]=[CH:20][CH:19]=1>>[CH3:1][NH:2][S:3]([C:6]1[CH:7]=[CH:8][C:9]([C:12]2=[N:13][NH:14][C:15](=[O:17])/[C:16]/2=[C:19]2\[NH:18][C:27]3[C:22]([CH:21]=[CH:20]\2)=[CH:23][CH:24]=[CH:25][CH:26]=3)=[CH:10][CH:11]=1)(=[O:4])=[O:5]

Participants

3

Reactant 2

HCID 15366Quinoline 1-oxideHCID 69053283HCID 69053283, compound

Product 1

HCID 178486268HCID 178486268, compound

Procedure

The title compound was synthesized using N-methyl-4-(5-oxo-4,5-dihydro-1H-pyrazol-3-yl)benzenesulfonamide and quinoline N-oxide according to the procedure described in Example 23. 1H NMR (400 MHz, DMSO-d6) δ ppm 2.49 (s, 3H) 7.09 (s, 1H) 7.48-7.60 (m, 2H) 7.76-7.81 (m, 3H) 7.83-7.90 (m, 4H) 8.25 (d, J=9.09 Hz, 2H) 11.90 (s, 1H); ESI-MS: m/z calc'd for C19H16N4O3S 380.42. found 381.2 (M+H)+.

Sources & evidence

ORD record
ord-668e25f98f7d4055ba879e0fb3ac884f
Source dataset
uspto-grants-2009_06
Patent number
US07550598B2

Reaction notes

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