Phenol, o-mercapto-(6CI,7CI,8CI) → HCID 178518875, compound

HRID 1987656Notes

Reaction equation

HRID 1987656 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5]/[C:4](=[C:12]2/[C:13](C)=[N:14][NH:15][C:16]/2=[O:17])/[CH:3]=1.[SH:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[OH:26]>>[OH:26][C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=1[S:19][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[NH:5]/[C:4](=[C:12]2/[CH:13]=[N:14][NH:15][C:16]/2=[O:17])/[CH:3]=1

Participants

3

Reactant 2

HCID 70718Phenol, o-mercapto-(6CI,7CI,8CI)HCID 178434119HCID 178434119, compound

Product 1

HCID 178518875HCID 178518875, compound

Procedure

The title compound was prepared from (Z)-4-(4-chloroquinolin-2(1H)-ylidene)-3-methyl-1H-pyrazol-5(4H)-one and 2-mercaptophenol using a procedure analogous to the one described in Example 6. 1H NMR (400 MHz, DMSO-D6) δ ppm 2.08 (s, 3H) 7.08 (s, 1H) 7.38-7.68 (m, 3H) 7.76-7.88 (m, 3H) 7.92 (d, J=8.14 Hz, 1H) 8.18 (d, J=8.24 Hz, 1H) 10.38 (s, 1H) 13.10 (bs, 1H); ESI-MS: m/z calc'd for C19H15N3O2S 349.09. found 350.3 (M+H)+.

Sources & evidence

ORD record
ord-4bf545739a4b4e61ba599e621ab9d1b4
Source dataset
uspto-grants-2009_06
Patent number
US07550598B2

Reaction notes

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