HCID 57725029, compound → HCID 23118293, compound

HRID 1987779Notes

Reaction equation

HRID 1987779 reaction equation
[N+:1]([C:4]1[C:5]([CH3:20])=[C:6]2[C:11](=[C:12]([CH3:15])[C:13]=1[CH3:14])[O:10][C:9]([CH2:17][O:18][CH3:19])([CH3:16])[CH:8]=[CH:7]2)([O-:3])=[O:2].[H][H]>C(O)C.[C].[Pd]>[N+:1]([C:4]1[C:5]([CH3:20])=[C:6]2[C:11](=[C:12]([CH3:15])[C:13]=1[CH3:14])[O:10][C:9]([CH2:17][O:18][CH3:19])([CH3:16])[CH2:8][CH2:7]2)([O-:3])=[O:2]

Participants

5

Reactant 2

HCID 57725029HCID 57725029, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 23118293HCID 23118293, compoundYield 100.3%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

9.4 g of 6-nitro-2-methoxymethyl-2,5,7,8-tetramethyl (2H) chromene was dissolved in 100 ml of ethanol and 1.0 g of a 10% palladium carbon catalyst was added and, after sealing hydrogen, the catalytic hydrogenation reaction was carried out at room temperature under normal pressure for 24 hours. After the completion of the reaction, the reaction solution was filtered and then concentrated under reduced pressure to obtain 9.5 g of the objective oily compound.

Workup

  1. customthe catalytic hydrogenation reaction
  2. customAfter the completion of the reaction
  3. filtrationthe reaction solution was filtered
  4. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-160361421d6547a99e483a764a5da299
Source dataset
uspto-grants-2009_06
Patent number
US07553837B2

Reaction notes

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