HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Benzodioxan-6-ylamine → 6-Bromo-naphthalene-2-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Benzodioxan-6-ylamine | HCID 89148 | — |
| Reactant | 6-Bromo-2-naphthalenecarboxylic acid | HCID 4549852 | — |
| Product | 6-Bromo-naphthalene-2-carboxylic acid (2,3-dihydro-benzo[1,4]dioxin-6-yl)-amide | HCID 11603400 | — |
Reaction Steps
This material was prepared analogous to the procedure described for Example 10(c). 6-Bromo-naphthalene-2-carboxylic acid (0.5 g, 2 mmol, Lancaster) reacted with 1,4-benzodioxan-6-amine (0.332 g, 2.2 mmol, Aldrich) to give the title compound as a light-yellow solid. Mp 222.7° C. MS (ESI, pos. ion) m/z: 384 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07553848B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-ec35b547b1aa4b0c87b9c9cd3cdb3e34 |
| Source note | uspto-grants-2009_06 |