HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-pyridinylcarbamate → 4-[N-(ethoxycarbonyl)amino]-1-[2-(3-methoxy-4-nitrophenyl)-2-oxoethyl]pyridinium bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-pyridinylcarbamate | HCID 766500 | — |
| Reactant | 2-Bromo-1-(3-methoxy-4-nitrophenyl)-1-ethanone | HCID 17957943 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-[N-(ethoxycarbonyl)amino]-1-[2-(3-methoxy-4-nitrophenyl)-2-oxoethyl]pyridinium bromide | HCID 86607555 | 100% |
Reaction Steps
This compound is prepared according to the same method as that described in Example 47, Step A by quaternization of 1.21 g (7.33 mmol) of ethyl 4-pyridinylcarbamate [described in J. Chem. Soc.; (1962), 2379-2381] with 2-bromo-1-(3-methoxy-4-nitrophenyl)-1-ethanone in dichloromethane. 3.24 g of a white precipitate are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07553845B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-800eba0e6b92468e9119f313b664d63f |
| Source note | uspto-grants-2009_06 |