Acetic Anhydride → HCID 86607559, compound

HRID 1987847Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[CH:4][N:5]2[C:9]([CH:10]=1)=[C:8]([C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:12])[C:7]([CH3:21])=[C:6]2[C:22](=[O:34])[C:23]1[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[C:25]([O:32][CH3:33])[CH:24]=1.[C:35](OC(=O)C)(=[O:37])[CH3:36]>>[C:35]([NH:1][C:2]1[CH:3]=[CH:4][N:5]2[C:9]([CH:10]=1)=[C:8]([C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=[O:12])[C:7]([CH3:21])=[C:6]2[C:22](=[O:34])[C:23]1[CH:28]=[CH:27][C:26]([N+:29]([O-:31])=[O:30])=[C:25]([O:32][CH3:33])[CH:24]=1)(=[O:37])[CH3:36]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 86607560HCID 86607560, compound

Product 1

HCID 86607559HCID 86607559, compound

Conditions

Temperature: 100 °C

Procedure

A suspension of 1.5 g (3.26 mmol) of benzyl [7-amino-3-(3-methoxy-4-nitrobenzoyl)-2-methylindolizin-1-yl]carboxylate in 10 mL of acetic anhydride is heated at 100° C. for 15 minutes.

Sources & evidence

ORD record: ord-d26a0caea1924a2dbd338e3317e0bca5
Source dataset: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07553845B2

Reaction notes

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