Ethyl bromoacetate → HCID 86607564, compound

HRID 1987851Notes

Reaction equation

[NH2:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]([C:8]2[N:16]3[C:11]([CH:12]=[CH:13][C:14]([OH:17])=[CH:15]3)=[C:10]([C:18]([O:20][CH3:21])=[O:19])[C:9]=2[CH3:22])=[O:7])=[CH:4][C:3]=1[O:25][CH3:26].Br[CH2:28][C:29]([O:31][CH2:32][CH3:33])=[O:30]>>[NH2:1][C:2]1[CH:24]=[CH:23][C:5]([C:6]([C:8]2[N:16]3[C:11]([CH:12]=[CH:13][C:14]([O:17][CH2:28][C:29]([O:31][CH2:32][CH3:33])=[O:30])=[CH:15]3)=[C:10]([C:18]([O:20][CH3:21])=[O:19])[C:9]=2[CH3:22])=[O:7])=[CH:4][C:3]=1[O:25][CH3:26]

Participants

Reactant 2

HCID 7748Ethyl bromoacetate

HCID 86607563HCID 86607563, compound

Product 1

HCID 86607564HCID 86607564, compound

Procedure

This compound is obtained by carrying out the procedure according to the preparation described in the example above, by alkylating methyl [3-(4-amino-3-methoxybenzoyl)-6-hydroxy-2-methylindolizin-1-yl]carboxylate with ethyl bromoacetate.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-eacfeada1fc84c31b27ec88469af730c
Source dataset: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07553845B2

Reaction notes

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