1,2-Dibromoethane → HCID 68902760, compound

HRID 1987888Notes

Reaction equation

HRID 1987888 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([C:7]([NH:9][C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][N:19]3[CH2:23][CH2:22][CH2:21][CH2:20]3)=[C:12]([O:24][CH3:25])[CH:11]=2)=[O:8])[NH:5][CH:6]=1.Br[CH2:27][CH2:28]Br>>[Br:1][C:2]1[CH:3]=[C:4]2[C:7](=[O:8])[N:9]([C:10]3[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][N:19]4[CH2:20][CH2:21][CH2:22][CH2:23]4)=[C:12]([O:24][CH3:25])[CH:11]=3)[CH2:28][CH2:27][N:5]2[CH:6]=1

Participants

3

Reactant 2

HCID 78391,2-DibromoethaneHCID 67215470HCID 67215470, compound

Product 1

HCID 68902760HCID 68902760, compoundYield 95%

Procedure

The title compound was prepared by alkylating the carboxamide of step B with 1,2-dibromoethane via the procedure described in step D of Example 1 in 95% yield. MS (ESI) 434, 436 (M+H)+.

Sources & evidence

ORD record
ord-eb22ebc46fc7407586832d2690d0773b
Source dataset
uspto-grants-2009_06
Patent number
US07553836B2

Reaction notes

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