1,2-Dibromoethane → HCID 24772545, compound

HRID 1987908Notes

Reaction equation

HRID 1987908 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:12]=[C:11]([C:13]([NH:15][C:16]3[CH:32]=[CH:31][C:19]([O:20][CH2:21][CH2:22][NH:23][C:24](=[O:30])[O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[C:18]([O:33][CH3:34])[CH:17]=3)=[O:14])[NH:10][CH:9]=2)=[CH:4][CH:3]=1.Br[CH2:36][CH2:37]Br>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:12]=[C:11]3[C:13](=[O:14])[N:15]([C:16]4[CH:32]=[CH:31][C:19]([O:20][CH2:21][CH2:22][NH:23][C:24](=[O:30])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[C:18]([O:33][CH3:34])[CH:17]=4)[CH2:37][CH2:36][N:10]3[CH:9]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 78391,2-DibromoethaneHCID 67215172HCID 67215172, compound

Product 1

HCID 24772545HCID 24772545, compound

Procedure

Following the procedure described in step D of Example 1, the above product of step B (55 mg) was alkylated with 1,2-dibromoethane to yield 7 mg of the title compound. MS (ESI) 456 (M+H)+.

Sources & evidence

ORD record
ord-dcadef93b07e4b13a35f2def77f287ff
Source dataset
uspto-grants-2009_06
Patent number
US07553836B2

Reaction notes

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