HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Dibromoethane → 7-(4-chlorophenyl)-2-(3-methoxy-4-(2-(tetrahydrofuran-2-yl)ethoxy)phenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Dibromoethane | HCID 7839 | — |
| Reactant | 4-(4-chlorophenyl)-N-(3-methoxy-4-(2-(tetrahydrofuran-2-yl)ethoxy)phenyl)-1H-pyrrole-2-carboxamide | HCID 67215186 | — |
| Product | 7-(4-chlorophenyl)-2-(3-methoxy-4-(2-(tetrahydrofuran-2-yl)ethoxy)phenyl)-3,4-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one | HCID 24772548 | — |
Reaction Steps
Following the procedure described in Example 1 step D, the product of step B (120 mg) was alkylated with 1,2-dibromoethane to yield 20 mg of the title compound. MS (ESI) 467 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07553836B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-45a7168a2a0745bea2d9480ee53f837e |
| Source note | uspto-grants-2009_06 |