HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 9-Oxo-9H-xanthene-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 9-oxoxanthene-3-carboxylate | HCID 473475 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 9-Oxo-9H-xanthene-3-carboxylic acid | HCID 473473 | — |
Reaction Steps
A solution of 9-oxo-9H-xanthene-3-carboxylic acid methyl ester (3.75 mmol) and 3 N sodium hydroxide (4.12 mmol) in MeOH (30 mL) was heated at reflux for 2 h. The solution was cooled to rt and made acidic with 2 N hydrochloric acid. The mixture was concentrated in vacuo, and then diluted with water. The resultant solid was collected by filtration, washed with water and air-dried to yield the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07553850B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-34f8d46f878f485ba8f91d5c46cf15d4 |
| Source note | uspto-grants-2009_06 |