4-Pyridinemethanamine → HCID 68831112, compound

HRID 1988098Notes

Reaction equation

[CH2:1]([C@@:3]12[CH2:16][C@:15]([OH:18])([CH3:17])[C@:14]([OH:25])([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:13][C@H:12]1[CH2:11][CH2:10][C:9]1[CH:8]=[C:7]([O:26][CH2:27][C:28](O)=[O:29])[CH:6]=[CH:5][C:4]2=1)[CH3:2].[NH2:31][CH2:32][C:33]1[CH:38]=[CH:37][N:36]=[CH:35][CH:34]=1>>[CH2:1]([C@@:3]12[CH2:16][C@:15]([OH:18])([CH3:17])[C@:14]([OH:25])([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:13][C@@H:12]1[CH2:11][CH2:10][C:9]1[CH:8]=[C:7]([O:26][CH2:27][C:28]([NH:31][CH2:32][C:33]3[CH:38]=[CH:37][N:36]=[CH:35][CH:34]=3)=[O:29])[CH:6]=[CH:5][C:4]2=1)[CH3:2]

Participants

Reactant 2

HCID 773174-Pyridinemethanamine

HCID 58742371HCID 58742371, compound

Product 1

HCID 68831112HCID 68831112, compound

Procedure

The title compound was prepared from the compound of Example 70 according to the procedure of Example 97 using 4-(aminomethyl)pyridine in place of 1-methylpiperazine. Mass spectrum (m/e) 501 (M++1).

Sources & evidence

ORD record: ord-116d460dcc16467f91ad079ee19fff7d
Source dataset: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07553877B2

Reaction notes

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