HCID 57729259, compound → HCID 57729260, compound

Participants

Reaction Steps

4-(4-Fluorophenyl)-7-(hydroxymethyl)-6-methyl-2H-chromen-2-one (0.487 g, 1.71 mmol) in CH2Cl2 (350 mL) was stirred with activated MnO2 (2.23 g, 25.7 mmol) for 65 h at rt. The reaction mixture was filtered through a pad of celite and the filtrate was concentrated to afford the title compound. 1H NMR (500 MHz, acetone-d6): δ 10.40 (s, 1H), 7.86 (s, 1H), 7.70 (m, 2H), 7.46 (s, 1H), 7.42 (m, 2H), 6.53 (s, 1H), 2.66 (s, 3H).

Provenance & Evidence