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HRID19882

反应详情

EQUATION

反应方程式

HRID 19882 的结构方程式

REACTANTS

反应物

3
结构：CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1
HCID11603838

未命名化合物

结构：CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCC(F)(F)CC4)n(-c4cncnc4)c3cc2Cl)CC1
HCID16739632

未命名化合物

结构：CC(C)N1CCC(Oc2cc3cc(C(=O)O)[nH]c3cc2Cl)CC1.Cl
HCID67017905

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCC(F)(F)CC4)[nH]c3cc2Cl)CC1
HCID67017927

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for the synthesis of intermediate 1, step 4, the title compound was synthesized from 6-chloro-5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid hydrochloride salt with 1 eq. lithium chloride (example 39, step 4). The title compound was obtained in 70% yield as light yellow solid. MS (m/e): 440.3 (MH+, 100%).