反应详情

Employing the same sequence as employed in the preparation of quinoline F3 but starting with the commercially available o-toluidene (Aldrich Chemical Co.) rather than 2-methylmercaptoaniline (F1) the desired quinoline I1 was obtained (1.24 g, 59% yield over two steps).

1. customwas obtained (1.24 g, 59% yield over two steps)