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HRID19887

反应详情

EQUATION

反应方程式

HRID 19887 的结构方程式

REACTANTS

反应物

2
结构：OB(O)c1ccnc(Cl)c1
HCID5151595

2-Chloro-4-pyridylboronic acid

C5H5BClNO2

结构：CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCOCC4)[nH]c3cc2Br)CC1
HCID67017918

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)N1CCC(Oc2cc3cc(C(=O)N4CCOCC4)n(-c4ccnc(Cl)c4)c3cc2Br)CC1
HCID16739659

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for the synthesis of example 6, the title compound was synthesized from [6-bromo-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-morpholin-4-yl-methanone (example 41, step 6) and 2-chloropyridine-4-boronic acid. The title compound was obtained in 12% yield as light yellow oil. MS (m/e): 561.4 (MH+, 100%).

WORKUP

后处理

  1. customIn analogy to the procedure described for the synthesis of example 6