Allyl bromide → HCID 11602988, compound

HRID 1988839Notes

Reaction equation

HRID 1988839 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][O:7][C:8]2[CH:13]=[CH:12][N:11]=[C:10]3[C:14]([CH3:18])=[C:15]([CH3:17])[NH:16][C:9]=23)=[CH:4][CH:3]=1.[CH2:21](Br)[CH:22]=[CH2:23]>>[ClH:1].[CH2:23]([N:16]1[C:9]2[C:10](=[N:11][CH:12]=[CH:13][C:8]=2[O:7][CH2:6][C:5]2[CH:19]=[CH:20][C:2]([Cl:1])=[CH:3][CH:4]=2)[C:14]([CH3:18])=[C:15]1[CH3:17])[CH:22]=[CH2:21]

Participants

3

Reactant 2

HCID 7841Allyl bromideHCID 687057517-[(4-Chlorophenyl)methoxy]-2,3-dimethyl-1H-pyrrolo[3,2-b]pyridine

Product 1

HCID 11602988HCID 11602988, compoundYield 75.3%

Procedure

In accordance with the same procedures as in Step 2 of Example 33, except for using 7-(4-chlorobenzyloxy)-2,3-dimethyl-1H-pyrrolo[3,2-b]pyridine prepared in Step 2 and allyl bromide, the titled compound was obtained as a white solid. (Yield: 75.3%

Sources & evidence

ORD record
ord-70e874c56f5f489c971584292057e050
Source dataset
uspto-grants-2010_01
Patent number
US07642269B2

Reaction notes

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