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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1988847Generated: November 4, 2026

3,5-Difluorobenzyl alcohol → 4-[(3,5-Difluorophenyl)methoxy]-3-nitropyridine

https://huagongshe.com/reaction/1988847

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Difluorobenzyl alcoholHCID 522721—
Reactant4-Chloro-3-nitropyridineHCID 2735781—
Product4-[(3,5-Difluorophenyl)methoxy]-3-nitropyridineHCID 6870486078%

Reaction Steps

In accordance with the same procedures as in Preparation 2, except for using 4-chloro-3-nitropyridine prepared in Step 1 of Preparation 1 and 3,5-difluorobenzyl alcohol, the titled compound was obtained as a yellow solid. (Yield: 78.0%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642269B2
Source datasetuspto-grants-2010_01
ORD IDord-69c17bbef72140f6ad636df971a3b42f
Source noteuspto-grants-2010_01