Benzylamine → N-Cyclopropyl-4-methyl-3-(1-{2-oxo-2-[(phenylmethyl)amino]ethyl}-1H-indazol-5-yl)benzamide

HRID 1988942Notes

Reaction equation

HRID 1988942 reaction equation
[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[CH:9][C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23]([O:25]C)=O)[N:17]=[CH:16]4)[CH:12]=2)=[O:6])[CH2:3][CH2:2]1.[CH2:28]([NH2:35])[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1>>[CH:1]1([NH:4][C:5](=[O:6])[C:7]2[CH:8]=[CH:9][C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23](=[O:25])[NH:35][CH2:28][C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[N:17]=[CH:16]4)[CH:12]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 58656497HCID 58656497, compound

Product 1

HCID 58656473N-Cyclopropyl-4-methyl-3-(1-{2-oxo-2-[(phenylmethyl)amino]ethyl}-1H-indazol-5-yl)benzamide

Procedure

Example 125 was prepared by General Method D using methyl (5-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-1H-indazol-1-yl)acetate (Example 117) and benzylamine to give the title compound (0.002 g),

Workup

  1. customExample 125 was prepared by General Method D

Sources & evidence

ORD record
ord-cc67a18856fb40429c8951c3cc719dc5
Source dataset
uspto-grants-2010_01
Patent number
US07642276B2

Reaction notes

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