Neopentylamine → HCID 58656457, compound

HRID 1988955Notes

Reaction equation

HRID 1988955 reaction equation
[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[C:9]([F:28])[C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23]([O:25]C)=O)[N:17]=[CH:16]4)[CH:12]=2)=[O:6])[CH2:3][CH2:2]1.[CH3:29][C:30]([CH3:34])([CH3:33])[CH2:31][NH2:32]>>[CH:1]1([NH:4][C:5](=[O:6])[C:7]2[CH:8]=[C:9]([F:28])[C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23]([NH:32][CH2:31][C:30]([CH3:34])([CH3:33])[CH3:29])=[O:25])[N:17]=[CH:16]4)[CH:12]=2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 79882NeopentylamineHCID 58656520HCID 58656520, compound

Product 1

HCID 58656457HCID 58656457, compound

Procedure

Example 140 was prepared by General Method D using methyl (5-{5-[(cyclopropylamino)carbonyl]-3-fluoro-2-methylphenyl}-1H-indazol-1-yl)acetate (Example 123) and 2,2-dimethyl-1-propanamine to give the title compound (0.008 g).

Workup

  1. customExample 140 was prepared by General Method D

Sources & evidence

ORD record
ord-b059ea9814514c549d2cb46352542998
Source dataset
uspto-grants-2010_01
Patent number
US07642276B2

Reaction notes

Loading…