Adipic Acid → HCID 21756589, compound

HRID 1988956Notes

Reaction equation

[C:1]([OH:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([OH:6])=[O:5].[C:9]([OH:18])(=[O:17])[CH2:10][CH2:11][CH2:12][CH2:13][C:14]([OH:16])=[O:15].COC(=O)CCCCC(O)=O.C[SiH](C)Cl.C[Si](/C(/C([O-])=O)=C(/[Si](Cl)(C)C)\C([O-])=O)(C)Cl.C[Si](OC(=O)CCCCC(O[Si](C)(C)Cl)=O)(C)Cl.COC(=O)C(C)([SiH2]Cl)C(C)CCC([O-])=O>>[C:1]([O-:8])(=[O:7])/[CH:2]=[CH:3]/[C:4]([O-:6])=[O:5].[C:9]([O-:18])(=[O:17])[CH2:10][CH2:11][CH2:12][CH2:13][C:14]([O-:16])=[O:15]

Participants

Reactant 7

HCID 196Adipic Acid

HCID 12328monoMethyl adipate

HCID 66108Chlorodimethylsilane

HCID 444972Fumaric Acid

HCID 86608727HCID 86608727, compound

HCID 86608729HCID 86608729, compound

HCID 131727834HCID 131727834, compound

Product 1

HCID 21756589HCID 21756589, compound

Procedure

Second, the end-capped macromer is synthesized. To prepare the macromer, fumaric acid, adipic acid, and adipic acid monomethyl ester are added to dimethylchlorosilane. Next, polycondensation of bis(dimethylchlorosilyl)-fumarate, bis(dimethylchlorosilyl)-adipate, and dimethylchlorosilyladipate monomethyl ester is carried out to obtain the fumarate-adipate macromer capped with adipic acid monomethyl ester at one end and with reactive chlorosilane at the other end. After completion of the polycondensation reaction, the reactive chlorosilane end of the macromer chains is quenched with excess methanol to obtain a macromer capped with adipic acid monomethyl ester and methoxysilane.

Workup

customSecond, the end-capped macromer is synthesized

Sources & evidence

ORD record: ord-a88304d5e7ec43528a5663addd253449
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07642300B2

Reaction notes

Loading…