1,4-Dioxa-8-azaspiro(4.5)decane → HCID 22056035, compound
Reaction equation
[O:1]1[C:5]2([CH2:10][CH2:9][NH:8][CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1.F[C:12]1[CH:13]=[CH:14][C:15]([N+:19]([O-:21])=[O:20])=[C:16]([NH2:18])[CH:17]=1>>[O:1]1[C:5]2([CH2:10][CH2:9][N:8]([C:12]3[CH:13]=[CH:14][C:15]([N+:19]([O-:21])=[O:20])=[C:16]([NH2:18])[CH:17]=3)[CH2:7][CH2:6]2)[O:4][CH2:3][CH2:2]1Participants
3
Procedure
The title compound was synthesized as described in Method 10, Step 2 from 1,4-dioxa-8-aza-spiro[4.5]decane and 5-fluoro-2-nitrophenylamine. LC/MS (m/z) 280.3 (MH+), Rt 2.41 minutes.
Sources & evidence
- ORD record
- ord-830909ff30514bf99d2f556940e719f3
- Source dataset
- uspto-grants-2010_01
- Patent number
- US07642278B2
Reaction notes
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