HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 4504275, compound → 2-(4-Bromo-imidazol-1-yl)-4-(4-chloro-phenyl)-6-trifluoromethyl-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 4504275 | HCID 4504275 | — |
| Reactant | HCID 178418934 | HCID 178418934 | — |
| Product | 2-(4-Bromo-imidazol-1-yl)-4-(4-chloro-phenyl)-6-trifluoromethyl-pyrimidine | HCID 57468726 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-(4-chloro-phenyl)-6-trifluoromethyl-pyrimidine (example A.1) (1.17 g, 4.0 mmol) and commercially available 4-bromo-imidazole (0.88 g, 6.0 mmol) according to the general procedure IVa. Obtained as an off-white solid (1.23 g, 76%). MS (EI) 404.0 [(M)+]; mp 247° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-3dce282fe9e14a8fb4a486e96d1c933a |
| Source note | uspto-grants-2010_01 |