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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1989157Generated: November 2, 2026

(3-Bromophenyl)boronic acid → 2-(3-Bromo-phenyl)-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridine

https://huagongshe.com/reaction/1989157

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Bromophenyl)boronic acidHCID 2734318—
ReactantHCID 57468624HCID 57468624—
Product2-(3-Bromo-phenyl)-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyridineHCID 57468744—

Reaction Steps

The title compound was prepared from 2-bromo-4-trifluoromethyl-6-(4-trifluoromethylphenyl)-pyridine (example A.19) (3.0 g, 8 mmol) and commercially available 3-bromo-benzeneboronic acid (1.954 g, 10 mmol) according to the general procedure IVb. Obtained as an orange oil (3.28 g, 91%). MS (ISP) 446.0 [(M+H)+] and 448.0 [(M+2+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642264B2
Source datasetuspto-grants-2010_01
ORD IDord-33ff2da822f14e88a7595029ed0678af
Source noteuspto-grants-2010_01