3,5-Dibromopyridine → 5'-Bromo-4-(4-chloro-phenyl)-6-methyl-[2,3']bipyridinyl

Participants

Reaction Steps

The title compound was prepared from 4-(4-chloro-phenyl)-2-iodo-6-methyl-pyridine (example A.29) (2.15 g, 6.5 mmol) and commercially available 3-bromo-pyridine-boronic acid [CAS-No. 452972-09-07] (alternatively prepared from commercially available 3,5-dibromopyridine according to Tetrahedron 2002, 58(17), 3323 or Synthesis 2003, (7), 1035) (1.448 g, 7.1 mmol) according to the general procedure IVb. Obtained as a white solid (1.35 g, 57%). MS (ISP) 358.9 [(M+H)+], 360.9 [(M+2+H)+] and 363.0 [(M+4+H)+].

Provenance & Evidence