HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Bromophenyl)boronic acid → 2-(3-Bromo-phenyl)-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Bromophenyl)boronic acid | HCID 2734318 | — |
| Reactant | 2-Chloro-4-(3,4-dichlorophenyl)-6-trifluoromethylpyrimidine | HCID 15477740 | — |
| Product | 2-(3-Bromo-phenyl)-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine | HCID 57468755 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-(3,4-dichloro-phenyl)-6-trifluoromethyl-pyrimidine (example A.7) (0.50 g, 1.53 mmol) and commercially available 3-bromo-benzene-boronic acid (0.40 g, 1.99 mmol) according to the general procedure IVb. Obtained as a light yellow oil (0.71 g, 83%). MS (EI) 447.7 [(M)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-ff5f452e30834aa2bd68bae7620b0794 |
| Source note | uspto-grants-2010_01 |