HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine-4-boronic acid → HCID 57468816, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine-4-boronic acid | HCID 5151595 | — |
| Reactant | 2-Chloro-4-(2-fluoro-4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidine | HCID 57468688 | — |
| Product | HCID 57468816 | HCID 57468816 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-(2-fluoro-4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidine (example A.61) (1.50 g, 4.35 mmol) and commercially available 2-chloro-pyridine-4-boronic acid (0.75 g, 4.8 mmol) according to the general procedure IVb. Obtained as a light red solid (0.64 g, 35%). MS (ISP) 422.0 [(M+H)+]; mp 146° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-682bee6e399f4490a96ab883469fe98f |
| Source note | uspto-grants-2010_01 |