HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 2-Imidazol-1-yl-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | 2-Chloro-4-trifluoromethyl-6-(4-trifluoromethylphenyl)-pyrimidine | HCID 57468599 | — |
| Product | 2-Imidazol-1-yl-4-trifluoromethyl-6-(4-trifluoromethyl-phenyl)-pyrimidine | HCID 57468847 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-(4-trifluoromethyl-phenyl)-6-trifluoromethyl-pyrimidine (example A.2) (0.16 g, 0.5 mmol) and commercially available imidazole (0.034 g, 0.5 mmol) according to the general procedure IVa. Obtained as a white solid (0.07 g, 39%). MS (EI) 358.0 [(M)+]; mp 162° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-4d1e508a8c7447f383fccbc3105760da |
| Source note | uspto-grants-2010_01 |