HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrole → 4-(4-Chloro-phenyl)-2-pyrrol-1-yl-6-trifluoromethyl-pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrole | HCID 8027 | — |
| Reactant | HCID 4504275 | HCID 4504275 | — |
| Product | 4-(4-Chloro-phenyl)-2-pyrrol-1-yl-6-trifluoromethyl-pyrimidine | HCID 57468849 | — |
Reaction Steps
The title compound was prepared from 2-chloro-4-(4-chloro-phenyl)-6-trifluoromethyl-pyrimidine (example A.1) (0.15 g, 0.5 mmol) and commercially available pyrrole (0.067 g, 1.0 mmol) according to the general procedure IVa. Obtained as a light brown solid (0.12 g, 74%). MS (EI) 323.1 [(M)+]; mp 128.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07642264B2 |
| Source dataset | uspto-grants-2010_01 |
| ORD ID | ord-6902111d89a545c1a2c0b147c488f3ec |
| Source note | uspto-grants-2010_01 |