2-Aminopyrimidine-5-boronic acid, pinacol ester → HCID 60209410, compound

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The title compound was prepared from 2-(4-bromo-imidazol-1-yl)-4-(3-trifluoromethylphenyl)-6-trifluoromethyl-pyrimidine (example E.57) (0.22 g, 0.5 mmol) and commercially available 2-amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (0.13 g, 0.6 mmol) according to the general procedure VI. Obtained as a yellow solid (0.106 g, 47%). MS (ISP) 452.0 [(M+H)+]; mp 223° C.

Provenance & Evidence